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lacuna

/ləˈkjuː.nə/ · la·cu·na
noun
  1. A gap or missing portion in a manuscript, text, or series. The editor noted a lacuna in the medieval chronicle where several pages had been lost.
  2. A small cavity or pit in an organ or tissue, especially in the brain. Neuroscientists observed a lacuna in the hippocampus that correlated with memory deficits.
  3. An omission or missing element in a logical argument or system. The philosopher pointed out a lacuna in the theory's explanation of consciousness.
Did you know? In genetics, a lacuna denotes a missing segment of DNA, showing how the word's original sense of a "gap" has been adopted across diverse scientific disciplines.
Written by Lexi Wordsworth, Dictionary Editor 2 lookups Added Aug 5, 2026